Chemical Studies on Bacterial Agglutination

نویسندگان

  • Michael Heidelberger
  • Elvin A. Kabat
چکیده

1. A method, conforming to the criteria of quantitative analytical chemistry, is described for the estimation of the agglutinin content of antisera. Examples are given of the application of the method to various antipneumococcus sera. 2. This new, absolute method is discussed with regard to its relation to the commonly used relative methods.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Mannose-contaminating agglutinin for Actinomyces viscosus and Actinomyces naeslundii.

Rapid agglutination of Actinomyces viscosus and Actinomyces naeslundii cells by D-mannose solutions was observed during studies of their attachment to mammalian cells in vitro. The specificity of the agglutination reaction was studied by slide agglutination tests and by measuring the rate of decrease in optical density of bacterial phosphate buffer suspensions caused by the setting of bacterial...

متن کامل

Multivalent Dendritic Molecules as Broad Spectrum Bacteria Agglutination Agents

This study reports the first set of synthetic molecules that act as broad spectrum agglutination agents and thus are complementary to the specific targeting of antibodies. The molecules have dendritic architecture and contain multiple copies of zinc(II)-dipicolylamine (ZnDPA) units that have selective affinity for the bacterial cell envelope. A series of molecular structures were evaluated, wit...

متن کامل

Sensitivity of passive bacterial agglutination for detection of hepatitis B surface antigen.

The sensitivity of passive bacterial agglutination (PBA), i.e., the agglutination of Staphylococcus aureus coated with antibodies to hepatitis B surface antigen by hepatitis B surface antigen, was assessed by testing reference panel no. 3A sera (Bureau of Biologics, U.S. Food and Drug Administration). Of the 23 samples containing hepatitis B surface antigen, 18 were positive by PBA. Sera from 1...

متن کامل

The Chemical Alteration of a Bacterial Surface, with Special Reference to the Agglutination of B. Proteus Ox-19

The chemical substitution of a bacterial surface has been effected by the addition of benzene sulfonyl chloride to B. proteus OX-19. The substitution of imidazole and amino groups on the bacteria has been followed by the microelectrophoretic method. Concomitant changes in the agglutinability of substituted organisms have been observed, without appreciable change in the antibody-combining capaci...

متن کامل

Agglutination of mouse erythrocytes by Eperythrozoon coccoides.

Erythrocytes from blood of mice infected with Eperythrozoon coccoides for 3 or 4 days agglutinated spontaneously. Washed E. coccoides particles agglutinated washed erythrocytes of uninfected mice. E. coccoides-mediated agglutination of normal mouse erythrocytes would be an excellent system for studies of bacterial adhesion.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Journal of Experimental Medicine

دوره 74  شماره 

صفحات  -

تاریخ انتشار 1936